| 2021-10-23 19:00:00October 23, 2021 |   APOLLON FC vs PAFOS FC | 19:00:007:00 pm | - | CYTA Championship | 2021-2022 | Tsireio StadiumTsireio Stadium, Limassol | Preview | 7η αγωνιστική |
| 2021-10-31 19:00:00October 31, 2021 |  OLYMPIAKOS LEFKOSIAS vs APOLLON FC | 19:00:007:00 pm | - | CYTA Championship | 2021-2022 | Makario StadiumNicosia, Cyprus | Preview | 8η αγωνιστική |
| 2021-11-05 18:00:00November 5, 2021 |  APOLLON FC vs DOXA KATOKOPIAS | 18:00:006:00 pm | - | CYTA Championship | 2021-2022 | Tsireio StadiumTsireio Stadium, Limassol | Preview | 9η αγωνιστική |
| 2021-11-22 18:00:00November 22, 2021 | APOLLON FC vs PAEEK | 18:00:006:00 pm | - | CYTA Championship | 2021-2022 | Tsireio StadiumTsireio Stadium, Limassol | Preview | 10η αγωνιστική |
| 2021-11-29 18:00:00November 29, 2021 | ANORTHOSIS FC vs APOLLON FC | 18:00:006:00 pm | - | CYTA Championship | 2021-2022 | Antonis PapadopoulosLarnaca, Cyprus | Preview | 11η αγωνιστική |
| 2021-12-06 19:00:00December 6, 2021 | ETHNIKOS ACHNAS FC vs APOLLON FC | 19:00:007:00 pm | - | CYTA Championship | 2021-2022 | Dasaki AchnasDasaki Achnas, Cyprus | Preview | 12η αγωνιστική |
| 2021-12-12 17:00:00December 12, 2021 | APOLLON FC vs ARIS LIMASSOL | 17:00:005:00 pm | - | CYTA Championship | 2021-2022 | Tsireio StadiumTsireio Stadium, Limassol | Preview | 13η αγωνιστική |
| 2021-12-19 19:00:00December 19, 2021 | APOEL FC vs APOLLON FC | 19:00:007:00 pm | - | CYTA Championship | 2021-2022 | GSPΛεωφόρος Παγκυπρίων, Strovolos, Cyprus | Preview | 14η αγωνιστική |
| 2022-01-02 19:00:00January 2, 2022 | APOLLON FC vs AEL FC | 19:00:007:00 pm | - | CYTA Championship | 2021-2022 | Tsireio StadiumTsireio Stadium, Limassol | Preview | 15η αγωνιστική |
| 2022-01-08 19:00:00January 8, 2022 |  AEK LARNACA FC vs APOLLON FC | 19:00:007:00 pm | - | CYTA Championship | 2021-2022 | | Preview | 16η αγωνιστική |
| 2022-01-15 19:00:00January 15, 2022 | APOLLON FC vs OMONOIA FC | 19:00:007:00 pm | - | CYTA Championship | 2021-2022 | Tsireio StadiumTsireio Stadium, Limassol | Preview | 17η αγωνιστική |
| 2022-01-22 19:00:00January 22, 2022 | PAFOS FC vs APOLLON FC | 19:00:007:00 pm | - | CYTA Championship | 2021-2022 | Stelios Kyriakides StadiumDemocracy Ave, Paphos, Cyprus | Preview | 18η αγωνιστική |
| 2022-01-29 19:00:00January 29, 2022 | APOLLON FC vs OLYMPIAKOS LEFKOSIAS | 19:00:007:00 pm | - | CYTA Championship | 2021-2022 | Tsireio StadiumTsireio Stadium, Limassol | Preview | 19η αγωνιστική |
| 2022-02-05 19:00:00February 5, 2022 | DOXA KATOKOPIAS vs APOLLON FC | 19:00:007:00 pm | - | CYTA Championship | 2021-2022 | Makario StadiumNicosia, Cyprus | Preview | 20η αγωνιστική |
| 2022-02-12 19:00:00February 12, 2022 | PAEEK vs APOLLON FC | 19:00:007:00 pm | - | CYTA Championship | 2021-2022 | Makario StadiumNicosia, Cyprus | Preview | 21η αγωνιστική |
| 2022-02-19 19:00:00February 19, 2022 | APOLLON FC vs ANORTHOSIS FC | 19:00:007:00 pm | - | CYTA Championship | 2021-2022 | Tsireio StadiumTsireio Stadium, Limassol | Preview | 22η αγωνιστική |
